Hydrochloric Acid → 6-Chloro-1-(propan-2-yl)-1H-indole-3-carboxylic acid

HRID 150228Notes

Reaction equation

[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:14]([C:15]([F:16])([F:17])[F:18])=[O:19])[cH:7][n:8]([CH:11]([CH3:12])[CH3:13])[c:9]2[cH:10]1.[ClH:22].[Na+:21].[OH-:20]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:14]([OH:19])=[O:20])[cH:7][n:8]([CH:11]([CH3:12])[CH3:13])[c:9]2[cH:10]1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 923Sodium ion

HCID 961Hydroxide

HCID 224972541-[6-Chloro-1-(1-methylethyl)-1H-indol-3-yl]-2,2,2-trifluoroethanone

Product 1

HCID 224972296-Chloro-1-(propan-2-yl)-1H-indole-3-carboxylic acid

Sources & evidence

ORD record: ord-ab6d3986743047ec836bc77828b7a143
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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