Sodium Hydroxide → HCID 69230210, compound

Participants

Reaction Steps

A solution of methyl 3-chloro-4-((4-methylpiperazin-1-yl)methyl)benzoate (270 mg, 0.96 mmol) in tetrahydrofuran was added to an aqueous sodium hydroxide solution (6 M, 1.5 mL) and the mixture was stirred at room temperature for 5 hours. The organic solvent was removed under reduced pressure and the residue was acidified with aqueous HCl until a white solid formed. The mixture was lyophilized to give a white solid (contained salt). LCMS (ESI): RT (min)=0.819, M+H+=268.8, method=B.

Provenance & Evidence