Lithium Hydroxide → HCID 57950908, compound

HRID 1502422Notes

Reaction equation

HRID 1502422 reaction equation
[CH2:1]([O:3][CH:4]1[CH2:6][CH:5]1[C:7]([O:9]CC)=[O:8])[CH3:2].[OH-].[Li+:13]>CO>[Li+:13].[CH2:1]([O:3][CH:4]1[CH2:6][CH:5]1[C:7]([O-:9])=[O:8])[CH3:2]

Participants

4

Reactant 2

HCID 3939Lithium HydroxideHCID 12731313HCID 12731313, compound

Product 1

HCID 57950908HCID 57950908, compoundYield 104%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of the crude ethyl 2-ethoxycyclopropanecarboxylate in methanol (10 mL) was treated with aqueous lithium hydroxide (8.6 mL, 1.0 M, 8.6 mmol, 1.0 equiv.), the mixture stirred at ambient temperature for 16 h, and concentrated in vacuo. The resulting orange syrup was twice redissolved in methanol and concentrated in vacuo to afford crude 2-ethoxycyclopropane-carboxylic acid lithium salt as an orange foam (1.21 g, 104%).

Workup

  1. concentrationconcentrated in vacuo
  2. dissolutionThe resulting orange syrup was twice redissolved in methanol
  3. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-c3da373b5aea4b11828c230b0c1ba810
Source dataset
uspto-grants-2015_12
Patent number
US09206175B2

Reaction notes

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