反应详情

A solution of the crude ethyl 2-ethoxycyclopropanecarboxylate in methanol (10 mL) was treated with aqueous lithium hydroxide (8.6 mL, 1.0 M, 8.6 mmol, 1.0 equiv.), the mixture stirred at ambient temperature for 16 h, and concentrated in vacuo. The resulting orange syrup was twice redissolved in methanol and concentrated in vacuo to afford crude 2-ethoxycyclopropane-carboxylic acid lithium salt as an orange foam (1.21 g, 104%).

1. concentrationconcentrated in vacuo
2. dissolutionThe resulting orange syrup was twice redissolved in methanol
3. concentrationconcentrated in vacuo