HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Sodium hydroxide rebamipide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Rebamipide | HCID 5042 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water | HCID 962 | — |
| Product | Sodium hydroxide rebamipide | HCID 68327531 | — |
Reaction Steps
24 ML of 10 N hydrochloric acid (2.8.4 g, 0.24 mol), 136 mL of purified water, and 400 mL of an aqueous solution containing 10% (w/v) HPMC (TC-5E) were mixed to prepare a hydrochloric acid-HPMC (TC-5E) solution. To 1400 mL of an aqueous solution of sodium hydroxide which was prepared by adding purified water to 8.8 g of sodium hydroxide (0.22 mol), 40 g of rebamipide (0.108 mol) was added and dissolved with heating to give a sodium hydroxide-rebamipide solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09211254B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-49589992ab724d9aa42277762247d0c0 |
| Source note | uspto-grants-2015_12 |