Hydrochloric Acid → Sodium hydroxide rebamipide

Participants

Reaction Steps

366 ML of 10 N hydrochloric acid (432 g, 3.66 mol) and 7.8 L of an aqueous solution containing 7.67% (w/v) HPMC (TC-5E) were mixed to prepare a hydrochloric acid-HPMC (TC-5E) solution. To 21 L of an aqueous solution of sodium hydroxide which was prepared by adding purified water to 132 g of sodium hydroxide (3.3 mol), 600 g of rebamipide (1.62 mol) was added and dissolved with heating to give a sodium hydroxide-rebamipide solution.

Provenance & Evidence