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HRID1502604

反应详情

EQUATION

反应方程式

HRID 1502604 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1
HCID5042

Rebamipide

C19H15ClN2O4

结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

2 次

PRODUCTS

生成物

1
结构：O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1.[Na+].[OH-]
HCID68327531

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

366 ML of 10 N hydrochloric acid (432 g, 3.66 mol) and 7.8 L of an aqueous solution containing 7.67% (w/v) HPMC (TC-5E) were mixed to prepare a hydrochloric acid-HPMC (TC-5E) solution. To 21 L of an aqueous solution of sodium hydroxide which was prepared by adding purified water to 132 g of sodium hydroxide (3.3 mol), 600 g of rebamipide (1.62 mol) was added and dissolved with heating to give a sodium hydroxide-rebamipide solution.

WORKUP

后处理

  1. additionwere mixed
  2. additionby adding
  3. additionwas added
  4. dissolutiondissolved
  5. temperaturewith heating