Methane → HCID 178427496, compound

Participants

Reaction Steps

103.6 mg (0.16 mmol) of 1-benzyl 5-(6-(3-tosylguanidino)hexyl) 2-(tert-butoxycarbonylamino)pentanedioate under nitrogen in MeOH. A few mg of 10% Palladium over activated charcoal were added. 3 vacuo hydrogen flush were done before stirring vigorously the reaction under a H2 atmosphere for 2 days. The reaction was filtered over celite and the solvent evaporated to give 74.4 mg of a colorless oil (yield=86%).

Provenance & Evidence