HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1503098Generated: October 31, 2026
Sodium Hydroxide → 2-Methyl-2-(2-(pyridin-4-yl)phenylthio)propanoic Acid
https://huagongshe.com/reaction/1503098
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 2-methyl-2-(2-(pyridin-4-yl)phenylthio)propanoate | HCID 68000733 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Methyl-2-(2-(pyridin-4-yl)phenylthio)propanoic Acid | HCID 54764232 | — |
Reaction Steps
A mixture of ethyl 2-methyl-2-(2-(pyridin-4-yl)phenylthio)propanoate and aqueous sodium hydroxide solution (1 M) in methanol is stirred at 60° C. for 12 hours. The reaction mixture is then concentrated, acidified, filtered and the isolated solid purified by to chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09212135B2 |
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| Source dataset | uspto-grants-2015_12 |
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| ORD ID | ord-acaf84286574495d8b7d30d3ac27e28f |
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| Source note | uspto-grants-2015_12 |
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