Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 86725371 | HCID 86725371 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 70558051 | HCID 70558051 | — |
Reaction Steps
To a solution of the product of Example 10A (1.3 g, 3.4 mmol) in dimethylsulfoxide (50 mL) was added ammonium hydroxide (5.2 mL, 34 mmol). The mixture was heated to 100° C. for 4 hours and was allowed to cool to ambient temperature. Water (50 mL) was added and the precipitate was filtered and washed with ethanol (20 mL) to give the title compound. MS: 364 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09212192B2 |
|---|
| Source dataset | uspto-grants-2015_12 |
|---|
| ORD ID | ord-e729f65787cf4b3da97c30eb08443c95 |
|---|
| Source note | uspto-grants-2015_12 |
|---|
