Dimethylformamide → 1-(pyridin-3-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

HRID 1504217Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1504217
CN([CH:4]=[O:5])C.[N:6]1[CH:11]=[CH:10][CH:9]=[C:8]([NH:12][C:13]2[C:14]([NH2:19])=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:7]=1>O>[N:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N:12]2[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[NH:19][C:4]2=[O:5])[CH:7]=1

Komponenten

4

Edukt 2

HCID 6228DimethylformamideHCID 22736684N-(3-pyridyl)-o-phenylenediamine

Produkt 1

HCID 200892131-(pyridin-3-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

N,N′-Carbonyldiimidazole(0.57 g) was added to a DMF solution (5 ml) of N-pyridine-3-ylbenzene-1,2-diamine(0.5 g). The mixture was stirred at room temperature for 1.5 hours. Water was added to the reaction mixture and the precipitated insoluble matter was separated, washed with water, and dried to give the title compound(0.5 g) as a pale whitish purple powder.

Aufarbeitung

  1. customthe precipitated insoluble matter was separated
  2. washwashed with water
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-16f3aefccb08408ab86e6e95bf45e8e9
Quelldatensatz
uspto-grants-2015_12
Patentnummer
US09212187B2

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