反应详情

5-(2,2-Dihydroxyethyl)-2-methyl-5H-furo[3,2-c]pyridine-4-one (2.1 g) and o-phenylenediamine(1.1 g) were suspended in ethanol(20 ml). Sodium hydrogensulfite(5.2 g) was added, and the mixture was heated and stirred overnight under reflux. The reaction mixture was cooled to room temperature. Water was added thereto and the precipitated insoluble matter was separated, washed with water, and dried to give the title compound(2.25 g).

1. temperaturethe mixture was heated
2. temperatureunder reflux
3. customthe precipitated insoluble matter was separated
4. washwashed with water
5. customdried