2,2-Dimethyloxan-4-ol → HCID 178426072, compound

HRID 1504396Notes

Reaction equation

HRID 1504396 reaction equation
[I-:1].[Zn+2:2].[I-].[CH3:4][C:5]1([CH3:12])[CH2:10][CH:9](O)[CH2:8][CH2:7][O:6]1>C1COCC1>[I-:1].[CH3:4][C:5]1([CH3:12])[CH2:10][CH:9]([Zn+:2])[CH2:8][CH2:7][O:6]1

Participants

4

Reactant 2

HCID 49146922,2-Dimethyloxan-4-olHCID 9883512zinc(II)iodide

Product 1

HCID 178426072HCID 178426072, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared in an analogous, manner to tetrahydro-2H-pyran-4-yl)zinc(II) iodide except that 2,2-dimethyltetrahydro-2H-pyran-4-ol (Combi Blocks) was used instead of tetrahydro-2H-pyran-4-ol in Step 1 to afford a 0.24M solution of (2,2-dimethyltetrahydro-2H-pyran-4-yl)zinc(II) iodide in THF.

Sources & evidence

ORD record
ord-dfb1f2cab3de4b96972761228deb4140
Source dataset
uspto-grants-2015_12
Patent number
US09212182B2

Reaction notes

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