HCID 80864926, compound → 3549-07-3

HRID 1504558Notes

Reaction equation

HRID 1504558 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[CH:10][N:9]=[C:8]([NH2:12])[CH:7]=2)[CH2:3][CH2:2]1>CC(C)CO>[CH2:4]([O:5][C:6]1[N:11]=[CH:10][N:9]=[C:8]([NH2:12])[CH:7]=1)[CH:1]([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 80864926HCID 80864926, compound

Product 1

HCID 680584683549-07-3Yield 76%

Reagents, catalysts & solvents 1

HCID 6560IsobutanolSolvent

Procedure

This was prepared in a manner analogous to 6-(cyclopropylmethoxy)pyrimidin-4-amine, where 2-methylpropan-1-ol was used as the alcohol. 6-isobutoxypyrimidin-4-amine (0.196 g, 1.172 mmol, 76% yield) was obtained as a white solid. m/z (ESI) 168.2 (M+H)+.

Sources & evidence

ORD record
ord-5e18af7030d5440a9a7ab9a86b333b8a
Source dataset
uspto-grants-2015_12
Patent number
US09212182B2

Reaction notes

Loading…