反应详情

In an acetic acid (1.6 mL) solvent, a suspension including syringaldehyde (300 mg, 1.65 mmol), hydantoin (198 mg, 1.98 mmol), and sodium acetate (405 mg, 4.94 mmol) was refluxed for 24 hours, and after cooling, the produced precipitate was filtered. The filtered solid was washed with methylene chloride and a small amount of water. After drying under reduced pressure, a target compound was obtained (192.9 mg, 44.3%).

1. temperaturewas refluxed for 24 hours
2. temperatureafter cooling
3. filtrationthe produced precipitate was filtered
4. washThe filtered solid was washed with methylene chloride
5. customAfter drying under reduced pressure
6. customa target compound was obtained (192.9 mg, 44.3%)