2-Chloro-4-aminopyrimidine → HCID 86731670, compound

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Reaction Steps

2-(2H-1,2,3-triazol-2-yl)pyrimidin-4-amine was prepared from 2-chloropyrimidin-4-amine using chemistry analogous to the synthesis of 6-methyl-4-(2H-1,2,3-triazol-2-yl)pyridin-2-amine (PrepEx 2.19 A). MS ESI calc'd. for C6H7N6 [M+H]+ 163. found 163. 1H NMR (500 MHz, DMSO-d6) δ 8.14 (d, J=5.5 Hz, 1H), 8.06 (s, 2H), 7.42 (s, 2H), 6.46 (d, J=5.5 Hz, 1H).

Provenance & Evidence