Iodoethane → HCID 117974075, compound

HRID 1504908Notes

Reaction equation

[CH3:1][CH:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[N:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1.[CH2:13]([I:15])[CH3:14]>>[I-:15].[CH2:13]([N+:8]1([CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH:2]2[CH3:1])[CH2:12][CH2:11][CH2:10][CH2:9]1)[CH3:14]

Participants

Reactant 2

HCID 6340Iodoethane

HCID 12218077HCID 12218077, compound

Product 1

HCID 117974075HCID 117974075, compound

Procedure

Using the same procedure described in examples 4 and 9 above, N-(2-methylcyclohexyl)pyrrolidine was quaternized with ethyl iodide to give N-ethyl-N-(2-methylcyclohexyl)pyrrolidinium iodide which ion-exchanged with hydroxide ion using the aforementioned exchange procedures to give the hydroxide solution of the N-ethyl-N-(2-methylcyclohexyl)pyrrolidinium in a combined yield 86% for both the quaternization and the exchange.

Sources & evidence

ORD record: ord-5f68f762b2624c13a6c3a52d757e394a
Source dataset: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09216911B2

Reaction notes

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