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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15051Generated: October 26, 2026

4-benzyloxy-1-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1H-pyridin-2-one → 4-[(e)-2-(4-Fluorophenyl)vinyl]-1-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1h-pyridin-2-one

https://huagongshe.com/reaction/15051

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-benzyloxy-1-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1H-pyridin-2-oneHCID 11502008—
Reactant4-[(E)-2-(4-fluorophenyl)vinyl]-2-(4-methoxybenzyloxy)-pyridineHCID 66872725—
Reactant4-[(e)-2-(4-Fluorophenyl)vinyl]-1h-pyridin-2-oneHCID 66872877—
Product4-[(e)-2-(4-Fluorophenyl)vinyl]-1-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1h-pyridin-2-oneHCID 11188891—

Reaction Steps

Operations similar to Steps (1), (2) and (3) of Example 12 were conducted except that 4-[(E)-2-(4-fluorophenyl)vinyl]-1H-pyridin-2-one was used in place of 4-benzyloxy-1H-pyridin-2-one in Example 12, to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732456B2
Source datasetuspto-grants-2010_06
ORD IDord-8b4f306bbce045648ac0402b91143577
Source noteuspto-grants-2010_06