Trifluoroacetic acid → HCID 58497933, compound

Participants

Reaction Steps

Similarly to example 14.2, the 5′-(3,5-Dichloro-phenyl)-5′-trifluoromethyl-4′,5′-dihydro-[3,3′]biisoxazolyl-5-carboxylic acid tert-butyl ester (393 mg) was deprotected with trifluoroacetic acid to give the 5′-(3,5-Dichloro-phenyl)-5′-trifluoromethyl-4′,5′-dihydro-[3,3′]biisoxazolyl-5-carboxylic acid (331 mg) as a white solid. 1H-NMR (CDCl3, 400 MHz): 7.65 (bs, 1H) 7.46 (m, 2H), 7.44-7.42 (m, 2H), 4.17 (d, 1H), 3.81 (d, 1H).

Provenance & Evidence