HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86673589, compound → HCID 67235532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86673589 | HCID 86673589 | — |
| Reactant | 1,1-dimethylethyl{(1R)-1-methyl-2-[(6-{[2-methyl-5-(methyloxy)phenyl]oxy}-3-pyridinyl)amino]-2-oxoethyl}carbamate | HCID 86673590 | — |
| Product | HCID 67235532 | HCID 67235532 | — |
Reaction Steps
The title compound was made in a similar fashion to the preparation of Intermediate 16 replacing {(1R)-1-methyl-2-[(4-{[2-methyl-5-(methyloxy)phenyl]oxy}phenyl)amino]-2-oxoethyl}carbamate with 1,1-dimethylethyl{(1R)-1-methyl-2-[(6-{[2-methyl-5-(methyloxy)phenyl]oxy}-3-pyridinyl)amino]-2-oxoethyl}carbamate (Intermediate 55, 150 mg) to afford the title compound (120 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216967B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-5e5ed91a8569428a956fed834df3bb0a |
| Source note | uspto-grants-2015_12 |