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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1505365Generated: October 31, 2026

HCID 67236226, compound → HCID 61147393, compound

https://huagongshe.com/reaction/1505365

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67236226HCID 67236226—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 61147393HCID 6114739387%

Reaction Steps

To a solution of 2-{[3-(1-methylethyl)phenyl]oxy}-5-nitropyrimidine (Intermediate 84, 520 mg) in methanol (50 mL) was added Pd/C (10% wt., 100 mg) and the mixture was stirred under H2 atmosphere for 3 hours. The resulting mixture was filtered through a pad of celite and the filtrate was concentrated under vacuum to afford the title compound (400 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09216967B2
Source datasetuspto-grants-2015_12
ORD IDord-df7224bb15a0480aa34a9c3a1ca6a600
Source noteuspto-grants-2015_12