Ethanol → HCID 67609650, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl-2-(4,5-dihydrofuran-3-yl)-2-oxoacetate (VI, 100 g) was dissolved in dichloromethane (500 ml) and Ethanol (150 mL) was added. The reaction mass was cooled to 5 to 10° C. N-bromosuccinimide (115 g) was added lot wise by maintaining temp below 10° C. Reaction mass was then stirred at 20-30° C. till completion of reaction. Reaction mass was washed with sodium bicarbonate solution (2%, 3×400 mL) and the organic layer was used for the next step.

Provenance & Evidence