HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → HCID 90229562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | Friluglanstat | HCID 71267445 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 90229562 | HCID 90229562 | — |
Reaction Steps
Methanesulfonic acid (1 Eq) was added to a suspension of N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-({[2-(trifluoromethyl)phenyl]carbonyl}amino)-1H-benzimidazole-4-carboxamide (250 mg) (obtained in Example 11) in MeOH (2 ml). After stirring for 30 minutes at room temperature, MeOH was removed under reduced pressure to obtain the titled compound as white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216968B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-039b0147477b427085044e1124acce8b |
| Source note | uspto-grants-2015_12 |