HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 136227340, compound → HCID 136341305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 136227340 | HCID 136227340 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 136341305 | HCID 136341305 | 100.1% |
Reaction Steps
Benzyl 3-(7H-pyrrolo[3,2-e][1,2,3]triazolo[1,5-c]pyrimidin-1-yl)piperidine-1-carboxylate (25.0 mg, 0.0664 mmol) in ethanol was stirred with 5% palladium-carbon (10 mg) under a hydrogen atmosphere at 50° C. for 2.5 hours. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound as a light brown solid (16.1 mg, yield quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216999B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-4c46ba158bb64394bc18a117615939a8 |
| Source note | uspto-grants-2015_12 |