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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1506473Generated: October 30, 2026

3-(1-methyl-7-vinyl-4,5-dihydro-1H-benzo[g]indazol-3-yl)-5-phenyl-4-(trifluoromethyl)isoxazole → 1-methyl-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydro-1H-benzo[g]indazole-7-carbaldehyde

https://huagongshe.com/reaction/1506473

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(1-methyl-7-vinyl-4,5-dihydro-1H-benzo[g]indazol-3-yl)-5-phenyl-4-(trifluoromethyl)isoxazoleHCID 67171177—
Reactant3-(4-Isobutyl-3-(trifluoromethyl)phenyl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehydeHCID 86669886—
Product1-methyl-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydro-1H-benzo[g]indazole-7-carbaldehydeHCID 86669919—

Reaction Steps

This compound was prepared according to the general procedure described for Preparation 23D, employing 50 mgs of 3-(1-methyl-7-vinyl-4,5-dihydro-1H-benzo[g]indazol-3-yl)-5-phenyl-4-(trifluoromethyl)isoxazole (78B). Yield: 48 mgs (96%); LC/MS M+1=424.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09216972B2
Source datasetuspto-grants-2015_12
ORD IDord-d22ca945b3204f62b2f48432ead516da
Source noteuspto-grants-2015_12