3-(3,4-Diethoxyphenyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole → 3-(3,4-Diethoxyphenyl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde

HRID 1506476Notes

Reaction equation

HRID 1506476 reaction equation
C(C1C=CC([C:11]2[O:15][N:14]=[C:13]3[C:16]4[C:21]([CH2:22][CH2:23][C:12]=23)=[CH:20][C:19]([CH:24]=[O:25])=[CH:18][CH:17]=4)=CC=1C(F)(F)F)C(C)C.[CH2:30]([O:32][C:33]1[CH:34]=[C:35](C2ON=C3C4C(CCC=23)=CC(C=C)=CC=4)[CH:36]=[CH:37][C:38]=1[O:39][CH2:40][CH3:41])[CH3:31]>>[CH2:40]([O:39][C:38]1[CH:37]=[C:36]([C:11]2[O:15][N:14]=[C:13]3[C:16]4[C:21]([CH2:22][CH2:23][C:12]=23)=[CH:20][C:19]([CH:24]=[O:25])=[CH:18][CH:17]=4)[CH:35]=[CH:34][C:33]=1[O:32][CH2:30][CH3:31])[CH3:41]

Participants

3

Reactant 2

HCID 671702973-(3,4-Diethoxyphenyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazoleHCID 866698863-(4-Isobutyl-3-(trifluoromethyl)phenyl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde

Product 1

HCID 866699213-(3,4-Diethoxyphenyl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde

Procedure

This compound was prepared according to the general procedure described for Preparation 23D, employing 67 mgs of 3-(3,4-diethoxyphenyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole (80A). Yield: 67 mgs (99%); LC/MS M+1=364.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-995df1017d814175a7a82f9d9f7cb796
Source dataset
uspto-grants-2015_12
Patent number
US09216972B2

Reaction notes

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