HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenyl-4-(trifluoromethyl)-5-(7-vinyl-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)isoxazole → 5-(7-(Oxiran-2-yl)-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)-3-phenyl-4-(trifluoromethyl)isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenyl-4-(trifluoromethyl)-5-(7-vinyl-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)isoxazole | HCID 67170584 | — |
| Reactant | 7-(Oxiran-2-yl)-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazole | HCID 86669878 | — |
| Product | 5-(7-(Oxiran-2-yl)-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)-3-phenyl-4-(trifluoromethyl)isoxazole | HCID 86669925 | — |
Reaction Steps
This compound was prepared according to the procedure described for Preparation 13A, employing 100 mgs of 3-phenyl-4-(trifluoromethyl)-5-(7-vinyl-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)isoxazole (82E). Yield: 100 mgs (96%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216972B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-d8d50049eb45474399c9d1f355ddca99 |
| Source note | uspto-grants-2015_12 |