HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Cyclohexyl-3-(trifluoromethyl)phenyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole → 3-(4-Cyclohexyl-3-(trifluoromethyl)phenyl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Cyclohexyl-3-(trifluoromethyl)phenyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole | HCID 67170984 | — |
| Reactant | 3-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde | HCID 86669930 | — |
| Product | 3-(4-Cyclohexyl-3-(trifluoromethyl)phenyl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde | HCID 86669933 | — |
Reaction Steps
The titled compound was prepared using the experimental protocol described for Preparation 89B employing 3-(4-cyclohexyl-3-(trifluoromethyl)phenyl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole (118D) as a starting material. The compound had an HPLC retention time=4.43 min. (condition C); LC/MS M+1=426.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216972B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-9353bc5fed3243dc9a58f90d5859a07c |
| Source note | uspto-grants-2015_12 |