HRID1506531

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)C(C)(CCc1ccc2c(c1)CCc1c-2noc1-c1noc(-c2ccccc2)c1C(F)(F)F)N=C(c1ccccc1)c1ccccc1

HCID86669932

未命名化合物

结构：CCOC(=O)C(CCc1ccc2c(c1)CCc1nc(-c3onc(-c4ccccc4)c3C(F)(F)F)sc1-2)N=C(c1ccccc1)c1ccccc1

HCID86669934

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C(C)(CCc1ccc2c(c1)CCc1nc(-c3onc(-c4ccccc4)c3C(F)(F)F)sc1-2)N=C(c1ccccc1)c1ccccc1

HCID86669935

未命名化合物

PROCEDURE

实验过程

The titled compound was prepared using the experimental protocol described for Preparation 93A employing ethyl 2-(diphenylmethyleneamino)-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoate (Preparation 119A) as a starting material. The compound had an LC/MS M+1=706.4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cf746641c0d24e84bfbc5b8803084826
来源数据集: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09216972B2
来源说明: uspto-grants-2015_12

反应 SMILES

[C:1]1([C:7](=[N:14][C:15]([CH3:51])([CH2:21][CH2:22][C:23]2[CH:24]=[C:25]3[C:48](=[CH:49][CH:50]=2)[C:29]2=NOC(C4C(C(F)(F)F)=C(C5C=CC=CC=5)ON=4)=[C:28]2[CH2:27][CH2:26]3)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C(=NC(CCC2C=C3C(=CC=2)C2[S:82][C:81]([C:87]4[O:91][N:90]=[C:89]([C:92]5[CH:97]=[CH:96][CH:95]=[CH:94][CH:93]=5)[C:88]=4[C:98]([F:101])([F:100])[F:99])=[N:80]C=2CC3)C(OCC)=O)C2C=CC=CC=2)C=CC=CC=1>>[C:8]1([C:7](=[N:14][C:15]([CH3:51])([CH2:21][CH2:22][C:23]2[CH:24]=[C:25]3[C:48](=[CH:49][CH:50]=2)[C:29]2[S:82][C:81]([C:87]4[O:91][N:90]=[C:89]([C:92]5[CH:97]=[CH:96][CH:95]=[CH:94][CH:93]=5)[C:88]=4[C:98]([F:101])([F:100])[F:99])=[N:80][C:28]=2[CH2:27][CH2:26]3)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1