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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1506531Generated: October 30, 2026

Ethyl 2-(diphenylmethyleneamino)-2-methyl-4-(3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazol-7-yl)butanoate → Ethyl 2-(diphenylmethyleneamino)-2-methyl-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoate

https://huagongshe.com/reaction/1506531

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(diphenylmethyleneamino)-2-methyl-4-(3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazol-7-yl)butanoateHCID 86669932—
ReactantEthyl 2-(diphenylmethyleneamino)-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoateHCID 86669934—
ProductEthyl 2-(diphenylmethyleneamino)-2-methyl-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoateHCID 86669935—

Reaction Steps

The titled compound was prepared using the experimental protocol described for Preparation 93A employing ethyl 2-(diphenylmethyleneamino)-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoate (Preparation 119A) as a starting material. The compound had an LC/MS M+1=706.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09216972B2
Source datasetuspto-grants-2015_12
ORD IDord-cf746641c0d24e84bfbc5b8803084826
Source noteuspto-grants-2015_12