HCID 67171291, compound → 3-(1-(5-fluoropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde

Participants

Role	Name	HCID	Charge
Reactant	HCID 67171291	HCID 67171291	—
Reactant	3-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde	HCID 86669930	—
Product	3-(1-(5-fluoropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-4,5-dihydronaphtho[1,2-c]isoxazole-7-carbaldehyde	HCID 86669937	—

Reaction Steps

The titled compound was prepared using the experimental protocol described for Preparation 89B employing 3-(1-(5-fluoropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole (122B) as a starting material. The compound had an HPLC retention time=3.56 min. (condition C); LC/MS M+1=428.9.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09216972B2
Source dataset	uspto-grants-2015_12
ORD ID	ord-f93097884c174c998ad0f4a832031c34
Source note	uspto-grants-2015_12