Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tributylvinyltin | HCID 81998 | — |
| Reactant | Lithium Chloride | HCID 433294 | — |
| Reactant | HCID 86669942 | HCID 86669942 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67169434 | HCID 67169434 | — |
Reaction Steps
To 3-(4-propylphenyl)-4,5-dihydro-3H-benzo[e]indazol-7-yl trifluoromethanesulfonate (Preparation 136D, 240 mg, 0.550 mmol) in dioxane was sequentially added tributyl(vinyl)stannane (0.178 mL, 0.605 mmol), lithium chloride (69.9 mg, 1.650 mmol) and tetrakis(triphenylphosphine)palladium(0) (38.1 mg, 0.033 mmol). Contents were purged with nitrogen gas for 5 min. and heated at 100° C. for 16 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09216972B2 |
|---|
| Source dataset | uspto-grants-2015_12 |
|---|
| ORD ID | ord-51bb6211c9b54ca7953f4a063d309e00 |
|---|
| Source note | uspto-grants-2015_12 |
|---|
