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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1506643Generated: November 2, 2026

(NZ)-N-[[2-(4-chlorophenyl)-1,3-oxazol-5-yl]methylidene]-2-methylpropane-2-sulfinamide → 1-(2-(4-Chlorophenyl)oxazol-5-yl)-2-(3,5-difluorophenyl)ethanamine hydrochloride

https://huagongshe.com/reaction/1506643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(NZ)-N-[[2-(4-chlorophenyl)-1,3-oxazol-5-yl]methylidene]-2-methylpropane-2-sulfinamideHCID 90280405—
Reactant(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamineHCID 90281432—
Product1-(2-(4-Chlorophenyl)oxazol-5-yl)-2-(3,5-difluorophenyl)ethanamine hydrochlorideHCID 90280320—

Reaction Steps

The title compound was prepared according to the method presented for the synthesis of compound 5E of Example 5 utilizing 19D. MS (m/z) 335.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09220710B2
Source datasetuspto-grants-2015_12
ORD IDord-fe89d246894a4f5686e66e8d8443319d
Source noteuspto-grants-2015_12