HuagongsheHuagongshe Chemistry Print Report · For research reference only
(NE)-N-[[5-(4-chlorophenyl)-1,3-oxazol-4-yl]methylidene]-2-methylpropane-2-sulfinamide → N-(1-(5-(4-chlorophenyl)oxazol-4-yl)-2-(3,5-difluorophenyl)ethyl)-2-methylpropane-2-sulfinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (NE)-N-[[5-(4-chlorophenyl)-1,3-oxazol-4-yl]methylidene]-2-methylpropane-2-sulfinamide | HCID 90280296 | — |
| Reactant | (R)-N-((1-(4-methoxyphenyl)-1H-imidazol-2-yl)methylene)-2-methylpropane-2-sulfinamide | HCID 90281518 | — |
| Reactant | HCID 178505920 | HCID 178505920 | — |
| Product | N-(1-(5-(4-chlorophenyl)oxazol-4-yl)-2-(3,5-difluorophenyl)ethyl)-2-methylpropane-2-sulfinamide | HCID 90280394 | — |
Reaction Steps
The title compound was prepared as a mixture of diastereomers according to the method presented for the synthesis of compound 5C and 5D of Example 5 utilizing 33E and (3,5-difluorobenzyl)magnesium bromide. MS (m/z) 438.9 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09220710B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-990c647ecb61421cbe744c97d5cfcaca |
| Source note | uspto-grants-2015_12 |