HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyrimidin-2-one → 4-(4-fluorobenzyloxy)-1-{4-[2-(1-pyrrolidinyl)-ethoxy]phenyl}-1H-pyrimidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyrimidin-2-one | HCID 68430376 | — |
| Reactant | 4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one | HCID 68431283 | — |
| Product | 4-(4-fluorobenzyloxy)-1-{4-[2-(1-pyrrolidinyl)-ethoxy]phenyl}-1H-pyrimidin-2-one | HCID 11704227 | — |
Reaction Steps
Step (3) of Example 12 was repeated except that 4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one was replaced with 4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyrimidin-2-one, to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732456B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-a9f8ad2f3b384e12a6b369833d155a12 |
| Source note | uspto-grants-2010_06 |