Dichloromethane → N-[4-(1-Methyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6(5H)-ylcarbonyl)phenyl]-2,4dichlorobenzamide

HRID 150670Notes

Reaction equation

HRID 150670 reaction equation
[CH3:1][c:2]1[n:3][n:4][c:5]2[n:6]1-[c:7]1[c:8]([cH:12][cH:13][cH:14][cH:15]1)[NH:9][CH2:10][CH2:11]2.[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[Cl:16][c:17]1[c:18]([C:19](=[O:20])[NH:21][c:22]2[cH:23][cH:24][c:25]([C:26](=[O:27])[Cl:28])[cH:29][cH:30]2)[cH:31][cH:32][c:33]([Cl:35])[cH:34]1.[Cl:43][CH2:44][Cl:45]>>[CH3:1][c:2]1[n:3][n:4][c:5]2[n:6]1-[c:7]1[c:8]([cH:12][cH:13][cH:14][cH:15]1)[N:9]([C:26]([c:25]1[cH:24][cH:23][c:22]([NH:21][C:19]([c:18]3[c:17]([Cl:16])[cH:34][c:33]([Cl:35])[cH:32][cH:31]3)=[O:20])[cH:30][cH:29]1)=[O:27])[CH2:10][CH2:11]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 116023454-[(2,4-dichlorobenzoyl)amino]benzoyl ChlorideHCID 120995541-methyl-5,6-dihydro-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepine

Product 1

HCID 54203046N-[4-(1-Methyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6(5H)-ylcarbonyl)phenyl]-2,4dichlorobenzamide

Sources & evidence

ORD record
ord-7c73681c23d5411f9fd9060d811e3777
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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