Pyridine → HCID 89907420, compound

Participants

Reaction Conditions

Reaction Steps

4.19 ml Trifluoroacetic anhydride is added dropwise to a solution of 3.25 g 6-chloro-4,4-dicyclohexyl-4H-benzo[1,3]dioxine-2-carboxylic amide and 1.7 ml pyridine in 29 ml dioxane at 0° C. The reaction was stirred for 30 min at 0° C. and for 4 h at room temperature. The reaction mixture was then poured on ice water and stirred for 30 min. The precipitate was filtered, washed with water and dried over P2O5 under vaccum. Yield: 2.95 g.

Provenance & Evidence