Water → HCID 60155536, compound

HRID 1506878Notes

Reaction equation

HRID 1506878 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([F:11])=[CH:4][C:3]=1[C:12](C)([C:18](OCC)=O)[C:13]([O:15]CC)=[O:14].S(=O)(=O)(O)O.O>C(O)(=O)C>[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[C:5]([F:11])=[CH:4][C:3]=1[CH:12]([CH3:18])[C:13]([OH:15])=[O:14]

Participants

5

Reactant 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 60155535HCID 60155535, compound

Product 1

HCID 60155536HCID 60155536, compoundYield 82.3%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of compound (26a) (10.8 g, 32.6 mmol) in acetic acid (36 mL), and concentrated sulfuric acid (10 mL), and water (26 mL) were treated in the same manner as in (b) in Production Example 1 to give 6.2 g (82%) of compound (27a) as yellow solid.

Sources & evidence

ORD record
ord-1adc797fed2e4e178ee24037cb52a4af
Source dataset
uspto-grants-2015_12
Patent number
US09221786B2

Reaction notes

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