HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-(2,6-Difluoro-4-nitrophenyl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 58280423 | HCID 58280423 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(2,6-Difluoro-4-nitrophenyl)propanoic acid | HCID 53429568 | 85.1% |
Reaction Steps
A solution of compound (26b) (7.8 g, 24.9 mmol) in acetic acid (28 mL), and concentrated sulfuric acid (8.0 mL), and water (20 mL) were treated in the same manner as in (b) in Production Example 1 to give 4.9 g (85%) of compound (27b) as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221786B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-97e23ef791194846ab73cdd4db5bd356 |
| Source note | uspto-grants-2015_12 |