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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15071Generated: October 28, 2026

4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyridin-2-one → HCID 58964877, compound

https://huagongshe.com/reaction/15071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyridin-2-oneHCID 67456822—
Reactant2-[(S)-2-fluoromethyl-1-pyrrolidinyl]ethanolHCID 68431178—
Reactant4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-oneHCID 68431283—
ProductHCID 58964877HCID 58964877—

Reaction Steps

Step (3) of Example 12 was repeated except that 4-benzyloxy-1-(4-hydroxyphenyl)-1H-pyridin-2-one and 2-(1-pyrrolidine)ethanol were replaced with 4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyridin-2-one (Step (2) of Example 28) and 2-[(S)-2-fluoromethyl-1-pyrrolidinyl]ethanol, respectively, to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732456B2
Source datasetuspto-grants-2010_06
ORD IDord-656d43bca27e48fc8c168823c40cbf39
Source noteuspto-grants-2010_06