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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507362Generated: October 30, 2026

2,3-Dichloro-6-methoxyquinoline → Ethyl 4-(3-chloro-6-methoxyquinolin-2-yl)cyclohex-3-enecarboxylate

https://huagongshe.com/reaction/1507362

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dichloro-6-methoxyquinolineHCID 39733293—
Reactant4-(4,4,5,5-Tetramethyl-(1,3,2)dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylic acid ethyl esterHCID 59278796—
ProductEthyl 4-(3-chloro-6-methoxyquinolin-2-yl)cyclohex-3-enecarboxylateHCID 66980116—

Reaction Steps

Followed Scheme 2, Step 1 (see Example 8, Step 1) starting from ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate and 2,3-dichloro-6-methoxyquinoline (Intermediate 4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221810B2
Source datasetuspto-grants-2015_12
ORD IDord-a5e9ec7846a04baa97d7748d3f572939
Source noteuspto-grants-2015_12