Isonicotinic Acid → HCID 73425720, compound
Reaction equation
[NH2:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH3:14])([CH3:13])[C:7](=[O:12])[N:8]2[CH3:11])=[CH:4][C:3]=1[F:15].[C:16](O)(=[O:23])[C:17]1[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=1>>[F:15][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:2]=1[NH:1][C:16](=[O:23])[C:17]1[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=1)[N:8]([CH3:11])[C:7](=[O:12])[C:6]2([CH3:13])[CH3:14]Participants
3
Procedure
Prepared in analogy to example 17 from 6-amino-5-fluoro-1,3,3-trimethylindolin-2-one and isonicotinic acid. The title compound was obtained as white powder.
Sources & evidence
- ORD record
- ord-f36d8b9bc7e64a61a506e586d799d65c
- Source dataset
- uspto-grants-2015_12
- Patent number
- US09221816B2
Reaction notes
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