Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507572Generated: October 31, 2026

3-Chloropyridine-4-carboxylic acid → 3-Chloro-N-(1-cyclopropyl-3,3-dimethyl-2-oxoindolin-6-yl)isonicotinamide

https://huagongshe.com/reaction/1507572

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloropyridine-4-carboxylic acidHCID 2735816—
Reactant6-Amino-1-cyclopropyl-3,3-dimethyl-1,3-dihydro-indol-2-oneHCID 118415185—
Product3-Chloro-N-(1-cyclopropyl-3,3-dimethyl-2-oxoindolin-6-yl)isonicotinamideHCID 73425827—

Reaction Steps

Prepared in analogy to example 26 from 3-chloroisonicotinic acid and 6-amino-1-cyclopropyl-3,3-dimethyl-1,3-dihydro-indol-2-one (example 14c). The title compound was obtained as white foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221816B2
Source datasetuspto-grants-2015_12
ORD IDord-a828bdbf0e664e8597a93931f2b5849f
Source noteuspto-grants-2015_12