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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507579Generated: October 31, 2026

3-Chloropyridine-4-carboxylic acid → 3-Chloro-N-(1-ethyl-3,3-dimethyl-2-oxoindolin-6-yl)isonicotinamide

https://huagongshe.com/reaction/1507579

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloropyridine-4-carboxylic acidHCID 2735816—
ReactantHCID 69068988HCID 69068988—
Product3-Chloro-N-(1-ethyl-3,3-dimethyl-2-oxoindolin-6-yl)isonicotinamideHCID 73425947—

Reaction Steps

Prepared in analogy to example 26 from 3-chloroisonicotinic acid and 6-amino-1-ethyl-3,3-dimethylindolin-2-one (G. Georges et al., US2006/142247 A1). The title compound was obtained as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221816B2
Source datasetuspto-grants-2015_12
ORD IDord-faa9b535ab434aa99ad0492f80cd87f2
Source noteuspto-grants-2015_12