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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507609Generated: October 26, 2026

2-Chloroisonicotinic acid → 2-Chloro-N-(1-cyclopropyl-3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-6-yl)isonicotinamide

https://huagongshe.com/reaction/1507609

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloroisonicotinic acidHCID 236985—
Reactant6-Amino-1-cyclopropyl-3,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-2(3H)-oneHCID 90047516—
Product2-Chloro-N-(1-cyclopropyl-3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-6-yl)isonicotinamideHCID 73426752—

Reaction Steps

Prepared in analogy to example 26 from 2-chloroisonicotinic acid and 6-amino-1-cyclopropyl-3,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-2(3H)-one (example 79c). The title compound was obtained as light yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221816B2
Source datasetuspto-grants-2015_12
ORD IDord-a37e2190d6de4adcaf08fa4effeed29e
Source noteuspto-grants-2015_12