4-Methoxyphenoxyacetic acid → 1-(4-(5-Amino-2-(4-(4-fluorophenyl)butyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-methoxyphenoxy)ethanone

Participants

Role	Name	HCID	Charge
Reactant	4-Methoxyphenoxyacetic acid	HCID 74649	—
Reactant	2-(4-(4-Fluorophenyl)butyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine	HCID 50942147	—
Product	1-(4-(5-Amino-2-(4-(4-fluorophenyl)butyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-methoxyphenoxy)ethanone	HCID 66758693	35%

Reaction Steps

This compound was prepared from 2-(4-(4-fluorophenyl)butyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-methoxyphenoxyacetic acid in a yield of 35%, according to the procedure for the synthesis of example 50.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09221822B2
Source dataset	uspto-grants-2015_12
ORD ID	ord-24dcb404706b49228ac4d935e65429f7
Source note	uspto-grants-2015_12