Trifluoroacetic acid → [3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl] 4-(7-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate
Reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[NH:9][C:8](=[O:12])[N:7]([CH:13]1[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][CH:22]([C:23]([N:24]3[CH2:25][CH2:26][CH:27]([N:30]4[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]4)[CH2:28][CH2:29]3)=[O:36])[CH2:37][c:38]3[cH:39][c:40]4[cH:41][n:42]([CH2:48][O:49][CH2:50][CH2:51][Si:52]([CH3:53])([CH3:54])[CH3:55])[n:43][c:44]4[c:45]([CH3:47])[cH:46]3)[CH2:17][CH2:18]1)[CH2:6]2.[OH:56][C:57]([C:58]([F:59])([F:60])[F:61])=[O:62]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[NH:9][C:8](=[O:12])[N:7]([CH:13]1[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][CH:22]([C:23]([N:24]3[CH2:25][CH2:26][CH:27]([N:30]4[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]4)[CH2:28][CH2:29]3)=[O:36])[CH2:37][c:38]3[cH:39][c:40]4[cH:41][n:42][nH:43][c:44]4[c:45]([CH3:47])[cH:46]3)[CH2:17][CH2:18]1)[CH2:6]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-4e26ef9adeab40a58c11e319e51659af
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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