Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 15734662 | HCID 15734662 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 71239270 | HCID 71239270 | — |
Reaction Steps
To a solution of 2-(2,4-dichlorophenyl)acrylic acid methyl ester (0.70 mmol) in 2 mL THF was added pyrrolidine (0.77 mmol) at 0° C. The reaction mixture was stirred at 0° C. for 50 min, diluted with DCM and washed with water. The organic layer was dried over MgSO4 and concentrated in vacuo to give the desired compound as pinkish oil;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09221832B2 |
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| Source dataset | uspto-grants-2015_12 |
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| ORD ID | ord-b45d0e0397444c31a5c1299951861095 |
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| Source note | uspto-grants-2015_12 |
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