HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-cyclopropylisonicotinic acid ethyl ester → HCID 71239378, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-cyclopropylisonicotinic acid ethyl ester | HCID 71239170 | — |
| Reactant | HCID 71239586 | HCID 71239586 | — |
| Product | HCID 71239378 | HCID 71239378 | — |
Reaction Steps
This compound was prepared using a method analogous to that of 5-hydroxyfuro[2,3-c]pyridazine-6-carboxylic acid ethyl ester (A.2.3.1), 3-chloro-2-cyclopropylisonicotinic acid ethyl ester replacing 3-chloropyridazine-4-carboxylic acid ethyl ester. Purification by CC (KP-SIL™ from Biotage) using Hept/EtOAc (7/3) gives the desired product as colorless oil;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221832B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-978fe5da0c004bcd98c03a56076e574c |
| Source note | uspto-grants-2015_12 |