HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylboronic acid → 4-cyclopropylfuro[2,3-c]pyridin-3(2H)-one O-methyl oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylboronic acid | HCID 2760897 | — |
| Reactant | 4-methylfuro[2,3-c]pyridin-3(2H)-one O-methyl oxime | HCID 86721925 | — |
| Product | 4-cyclopropylfuro[2,3-c]pyridin-3(2H)-one O-methyl oxime | HCID 86721927 | — |
Reaction Steps
This compound was prepared using a method analogous to that of 4-methylfuro[2,3-c]pyridin-3(2H)-one O-methyl oxime (A.2.11.4), cyclopropylboronic acid replacing trimethylboroxine. Purification by CC using Hept/EtOAc (9/1 to 8/2) gives the desired product as white solid;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221832B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-a7b15b5e71ed4be5a75468572d555b6c |
| Source note | uspto-grants-2015_12 |