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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1508254Generated: October 31, 2026

Sodium Methoxide → 2-Chloro-4-methoxy-6-methylnicotinic acid ethyl ester

https://huagongshe.com/reaction/1508254

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium MethoxideHCID 10942334—
ReactantEthyl 2-chloro-4-ethoxy-6-methylpyridine-3-carboxylateHCID 52911135—
Product2-Chloro-4-methoxy-6-methylnicotinic acid ethyl esterHCID 13933642—

Reaction Steps

This compound was prepared using a method analogous to that of 2-chloro-4-ethoxy-6-methylnicotinic acid ethyl ester (A.2.17.1), NaOMe replacing NaOEt;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221832B2
Source datasetuspto-grants-2015_12
ORD IDord-b119553329394bf4bf3886ff552b17e9
Source noteuspto-grants-2015_12